Diethyl (Ethoxycarbonyl)phosphonate

CAS: 1474-78-8

Ref. TR-D444325

Produktinformation

• Name: Diethyl (Ethoxycarbonyl)phosphonate
• Synonyme: Foscarnet Sodium Hexahydrate Imp. D (EP), Foscarnet Imp. D (EP), Foscarnet USP Related Compound D, Foscarnet USP RC D, Phosphinecarboxylic acid, 1,1-diethoxy-, ethyl ester, 1-oxide, Formic acid, phosphono-, triethyl ester (7CI,8CI), Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide (9CI), Diethyl carbethoxyphosphonate, Ethyl diethylphosphonoformate, NSC 108684, Triethyl carboxyphosphonate, Triethyl phosphonoformate, Ethyl (Diethoxyphosphoryl)formate, O,O-Diethyl ethoxycarbonylphosphonate, Foscarnet Related Compound D, Foscarnet Sodium Hexahydrate Impurity D, Foscarnet Impurity D, Diethyl (ethoxycarbonyl)phosphonate, Ethyl Diethoxyphosphanecarboxylate Oxide, Formic acid, phosphono-, triethyl ester, Phosphinecarboxylic acid, 1,1-diethoxy-, ethyl ester, 1-oxide, Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide, Phosphonoformic acid Triethylester = Ethyl diethoxy Phosphinylformate

Beschreibung

Stability Moisture Sensitive
Applications Diethyl (Ethoxycarbonyl)phosphonate is an impurity in the synthesis of Foscarnet (F727400), an inhibitor of viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral.
References Helgstrand, E., et al.: Science, 201, 819 (1978), Reno, J.M., et al.: Antimicrob. Agents Chemother., 13, 188, (1978), Alenius, S., et al.: Arch. Virol., 60, 197 (1979),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 210.16
• Formel: C₇H₁₅O₅P
• Farbe/Form: Neat
• InChl: InChI=1S/C7H15O5P/c1-4-10-7(8)13(9,11-5-2)12-6-3/h4-6H2,1-3H3
• InChI Key: InChIKey=NOJFJZZMRDSOLM-UHFFFAOYSA-N
• SMILES: CCOC(=O)P(=O)(OCC)OCC