N-Desmethoxypropyl Prucalopride

CAS: 137211-64-4

Ref. TR-D446943

Produktinformation

• Name: N-Desmethoxypropyl Prucalopride
• Synonyme: 4-Amino-5-chloro-2,3-dihydro-N-4-piperidinyl-7-benzofurancarboxamide

Beschreibung

Applications N-Desmethoxypropyl Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 132.201
• Formel: C₁₄H₁₈ClN₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C14H18ClN3O2/c15-11-7-10(13-9(12(11)16)3-6-20-13)14(19)18-8-1-4-17-5-2-8/h7-8,17H,1-6,16H2,(H,18,19)
• InChI Key: InChIKey=XKPTXCDASJWOLK-UHFFFAOYSA-N
• SMILES: CCCOC(C)OCC