N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride

CAS: 182808-16-8

Ref. TR-D446953

Produktinformation

• Name: N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride
• Synonyme: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxamide
• Marke: TRC
• Beschreibung: Applications N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

Chemische Eigenschaften

• Molekulargewicht: 225.383
• Formel: C₉H₉ClN₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C9H9ClN2O2/c10-6-3-5(9(12)13)8-4(7(6)11)1-2-14-8/h3H,1-2,11H2,(H2,12,13)
• InChI Key: InChIKey=PVXPIJICTUHMAO-WJDAMSDJSA-N
• SMILES: [2H]C([2H])(CCCC(=O)OC)C1([2H])SSCC1([2H])[2H]