(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid

CAS: 220352-36-3

Ref. TR-D447015

Produktinformation

• Name: (1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid
• Synonyme: trans-2-(3,4-Difluoro-phenyl)-cyclopropanecarboxylic Acid, (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxylic acid

Beschreibung

Applications (1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarboxylic Acid is an intermediate used to prepare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis. It is also used to synthesize triazolopyrimidine derivatives as P2T receptor antagonists.
References Springthorpe, B., et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007); Guile, S., et al.: PCT Int. Appl., WO 9905143 A1 19990204 (1999)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 198.17
• Formel: C₁₀H₈F₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C10H8F2O2/c11-8-2-1-5(3-9(8)12)6-4-7(6)10(13)14/h1-3,6-7H,4H2,(H,13,14)/t6-,7+/m0/s1