Nadolol Impurity C (Mixture)

Ref. TR-D447570

Produktinformation

• Name: Nadolol Impurity C (Mixture)
• Synonyme: 1,3-Bis[cis-6,7-dihydroxy-5,6,7,8-tetrahydronaphthalene-1-yloxy]propan-2-ol, Mixture of (2SR,3RS)-5-(3-{[(6RS,7SR)-6,7-Dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]oxy}-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol and 1,3-Bis[(6R,7S)-6,7-dihydroxy-5,6,7,8-tetrahydronaphthalene-1-yloxy]propane-2-ol, 5,5'-[(2-Hydroxypropane-1,3-diyl)-bis(oxy)]bis(cis-1,2,3,4-tetrahydronaphthalene-2,3-diol), rel-(2S,3R)-5-[3-[(rel-(6R,7S)- 6,7-Dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol

Beschreibung

Applications (2S,3R)-5-(3-(((6R,7S)-6,7-Dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)oxy)-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol is an impurity of Nadolol (N201050), a β-Adrenergic blocker. Antihypertensive; antianginal.
References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977); Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978); Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 416.46
• Formel: C₂₃H₂₈O₇
• Farbe/Form: Mixture
• InChl: InChI=1S/C23H28O7/c24-15(11-29-22-5-1-3-13-7-18(25)20(27)9-16(13)22)12-30-23-6-2-4-14-8-19(26)21(28)10-17(14)23/h1-6,15,18-21,24-28H,7-12H2/t15?,18-,19+,20+,21-
• InChI Key: InChIKey=ICMQRBPJEHVDOL-XNKYAEKGSA-N
• SMILES: OC(COc1cccc2c1C[C@@H](O)[C@@H](O)C2)COc1cccc2c1C[C@@H](O)[C@@H](O)C2.OC(COc1cccc2c1C[C@H](O)[C@H](O)C2)COc1cccc2c1C[C@@H](O)[C@@H](O)C2