b-Dihydrothevinone

CAS: 16196-83-1

Ref. TR-D449843

Produktinformation

• Name: b-Dihydrothevinone
• Synonyme: 7beta-Acetyl-6,14-endo-ethanotetrahydrothebaine, 1-[(5alpha,7beta)-4,5-Epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]-ethanone, 1-[(5alpha,7beta)-4,5-Epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]-ethanone
• CAS: 16196-83-1

Beschreibung

Applications β-Dihydrothevinone is an intermediate in synthesizing 7-(S)-Buprenorphine (B689765), which is a controlled substance (narcotic). Analgesic that demonstrates narcotic agonist-antagonist properties.
References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976); Rance, M.J., Biochem. Pharmacol., 25, 735 (1976); Heel, R.C., et al.: Drugs, 17, 81 (1979);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 383.48
• Formel: C₂₃H₂₉NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C23H29NO4/c1-13(25)15-12-21-7-8-23(15,27-4)20-22(21)9-10-24(2)17(21)11-14-5-6-16(26-3)19(28-20)18(14)22/h5-6,15,17,20H,7-12H2,1-4H3/t15-,17+,20+,21+,22-,23+/m0/s1
• InChI Key: InChIKey=KRWAWNXEYPCCLG-WKUBJUINSA-N
• SMILES: COc1ccc2c3c1O[C@@H]1[C@]34CCN(C)[C@H](C2)[C@]42CC[C@@]1(OC)[C@H](C(C)=O)C2