5,6-Dihydro CP-690550

CAS: 1640972-35-5

Ref. TR-D450240

Produktinformation

• Name: 5,6-Dihydro CP-690550
• Synonyme: 3-((3R,4R)-3-((6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile

Beschreibung

Applications 5,6-Dihydro CP-690550 is an impurity of CP-690550 (C781350), a pyrrolo[2,3-d]pyrimidine derivative, as Janus kinase inhibitor for treatment of rheumatoid arthritis.
References Sheiner, L., et al.: Clin. Pharmacol. Ther., 25, 358 (1979); Dayneka, N., et al.: J. Pharmacokin. Biopharm., 21, 457 (1993); Changelian, P., et al.: Science, 302, 875 (2003); Lee, H., et al.: Clin. Pharmacol. Ther., 73, 348 (2003); Hutmacher, M., et al.: J. Clin. Pharmacol., 47, 238 (2007)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 314.39
• Formel: C₁₆H₂₂N₆O
• Farbe/Form: Neat
• SMILES: C[C@@H]1CCN(C(=O)CC#N)C[C@@H]1N(C)c1ncnc2c1CCN2