(±)-3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile

CAS: 51491-09-9

Ref. TR-D450570

Produktinformation

• Name: (±)-3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile
• Synonyme: 3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile
• Marke: TRC
• Beschreibung: Applications (±)-3',4'-Dihydro-1'-hydroxy-7'-methoxy-spiro[cyclopentane-1,2'(1'H)-naphthalene]-1'-acetonitrile is an intermediate in the synthesis of rac-14-epi-Dextromethorphan (D299440), which is an analog of Dextromethorphan (D299445) which is an antitussive compound showing analgesic properties. Dextromethorphan is used in cough medication formulations.References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007)

Chemische Eigenschaften

• Molekulargewicht: 271.35
• Formel: C₁₇H₂₁NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C17H21NO2/c1-20-14-5-4-13-6-9-16(7-2-3-8-16)17(19,10-11-18)15(13)12-14/h4-5,12,19H,2-3,6-10H2,1H3
• InChI Key: InChIKey=JHSLVEQWBDYFQN-LURJTMIESA-N
• SMILES: CN1C[C@@H](C(=O)OC(C)(C)C)NC1=O