(+)-α-Dihydrotetrabenazine-13C2D6

CAS: 85081-18-1

Ref. TR-D453617

Produktinformation

• Name: (+)-α-Dihydrotetrabenazine-13C2D6
• Synonyme: (2R,3R,11bR)-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol-13C2D6, [2R-(2α,3β,11bβ)]-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol-13C2D6, (+)-(2R,3R,11bR)-Dihydrotetrabenazine-13C2D6, (+)-DTBZ-13C2D6, (+)-Dihydrotetrabenazine-13C2D6, (2R,3R,11bR)-DHTBZ-13C2D6
• Marke: TRC
• Beschreibung: Applications (+)-α-Dihydrotetrabenazine-13C2D6 is the isotope labelled analog of (+)-α-Dihydrotetrabenazine (D453615); a potent inhibitor of vascular monoamine transporter 2 (VMAT2) and an agent of significant interest for therapeutic and molecular imaging applications.References Yao, Z., et al.: Eur. J. Med. Chem., 46, 1841 (2011); Rishel, M.J., et al.: J. Org. Chem., 74, 4001 (2009)

Chemische Eigenschaften

• Molekulargewicht: 327.461
• Formel: C₂C₁₇D₆H₂₃NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3/t14-,16-,17-/m1/s1/i3+1D3,4+1D3
• InChI Key: InChIKey=WEQLWGNDNRARGE-SZCZRRBZSA-N
• SMILES: [2H][13C]([2H])([2H])Oc1cc2c(cc1O[13C]([2H])([2H])[2H])[C@H]1C[C@@H](O)[C@H](CC(C)C)CN1CC2