10,17β-Dihydroxy-estra-1,4-dien-3-one

CAS: 549-02-0

Ref. TR-D454120

Produktinformation

• Name: 10,17β-Dihydroxy-estra-1,4-dien-3-one
• Synonyme: 10,17beta-Dihydroxy-estra-1,4-dien-3-one

Beschreibung

Applications 10,17β-Dihydroxy-estra-1,4-dien-3-one is a prodrug that can be converted to the main human estrogen, 17β-estradiol, in the brain and not elsewhere in the body due to an enzyme expressed only in the brain. It provides positive estrogenic effects on the brain and relieve symptoms in patients with a broad range of central nervous system diseases without side effects in other tissues.
References Prokai, L., et al.: Sci. Transl. Med., 7, 297 (2015)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 288.381
• Formel: C₁₈H₂₄O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C18H24O3/c1-17-8-7-15-13(14(17)4-5-16(17)20)3-2-11-10-12(19)6-9-18(11,15)21/h6,9-10,13-16,20-21H,2-5,7-8H2,1H3/t13-,14-,15-,16-,17-,18+/m0/s1
• InChI Key: InChIKey=UIKDFTLKOKNUJP-UHFFFAOYSA-N
• SMILES: CC12CCC3C(CCC4=CC(=O)C=CC43O)C1CCC2O