Dimenhydrinate

CAS: 523-87-5

Ref. TR-D460520

Produktinformation

• Name: Dimenhydrinate
• Synonyme: 1H-Purine-2,6-dione, 8-chloro-3,7-dihydro-1,3-dimethyl-, compd. with 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), Theophylline, 8-chloro-, compd. with 2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1) (7CI,8CI), Ethanamine, 2-(diphenylmethoxy)-N,N-dimethyl-, compd. with 8-chloro-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1) (9CI), Ethylamine, 2-(diphenylmethoxy)-N,N-dimethyl-, compd. with 8-chlorotheophylline (1:1) (8CI), 2-(Diphenylmethoxy)-N,N-dimethylethylamine 8-chlorotheophyllinate, Amosyt, Anautine, Andramine, Antemin, Aviomarin, Chloranautine, Diamarin, Dimate, Dimigal, Diphenhydramine 8-chlorotheophyllinate, Diphenhydrinate, Dommanate, Dramamin, Dramamine, Dramarin, Dramina, Dramocen, Dramyl, Dromyl, Emedyl, Emes, Epha, Faston, Gravinol, Gravinol (antiemetic), Gravol, Menhydrinate, NSC 117855, Neo-Navigan, Novamin, Novamine, Permital, Reidamine, Reise-Engletten, Removine, Supremal, Teodramin, Theohydramine, Travel-Gum, Travelin, Travelmin, Vomex A
• Marke: TRC
• Beschreibung: Stability HygroscopicApplications An antihistamine with antiemetic properties used to prevent nausea and motion sicknes composed of two drugs 8-Chlorotheophylline (C411440) and Diphenhydramine (D486900).References Sibel, K. et al.: Arzneim.-Forsch. , 52, 529 (2002); Pytel, J. et al.: Clin. Therap., 29, 84 (2007); Scholtz, A.W. et al.: Clin. Therap., 26, 866 (2004)

Chemische Eigenschaften

• Molekulargewicht: 469.96
• Formel: C₁₇H₂₁NO·C₇H₇ClN₄O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h3-12,17H,13-14H2,1-2H3;1-2H3,(H,9,10)
• InChI Key: InChIKey=NFLLKCVHYJRNRH-UHFFFAOYSA-N
• SMILES: CN(C)CCOC(c1ccccc1)c1ccccc1.Cn1c(=O)c2nc(Cl)[nH]c2n(C)c1=O