Dimethyl Fumarate-d2

CAS: 23057-98-9

Ref. TR-D464967

Produktinformation

• Name: Dimethyl Fumarate-d2
• Synonyme: Fumaric-d2 Acid Dimethyl Ester, (2E)-2-Butenedioic-2,3-d2 Acid Dimethyl Ester, (E)-2-Butenedioic-2,3-d2 Acid Dimethyl Ester, 2-Butenedioic-2,3-d2acid, dimethyl ester, (2E)- (9CI), 2-Butenedioic-2,3-d2 acid, dimethyl ester,(E)-, Fumaric-d2 acid, dimethyl ester (8CI), Dimethyl fumarate-d2

Beschreibung

Applications Labelled Dimethyl Fumarate (D464965). Dimethyl Fumarate is the methyl ester form of Fumaric Acid (F500380), and is a compound used as a treatment for the relapsing forms of multiple sclerosis and psoriasis. Dimethyl Fumarate is effective in treating multiple sclerosis by mediating the activation of the nuclear 1 factor (Nrf2) antioxidant response pathway, resulting in neuroprotective effects. Dimethyl Fumarate is also used in cycloaddition reactions involving ylides, benzenes and amino acids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Albrecht, P., et al.: J. Neuroinflammation, 9, 2094 (2012); Chen, X. et al.: J. Am. Chem. Soc., 130, 5652 (2008); Gold, R., et al.: New Engl. J Med., 367, 1098 (2012); Gothelf, A. et al.: Angew. Chem., Int. Ed., 41, 4236 (2002); Schmidt, T., et al.: Bioorg. Med. Chem., 15, 333 (2007)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 146.14
• Formel: C₆H₆D₂O₄
• Farbe/Form: Off White
• InChl: InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+/i3D,4D
• InChI Key: InChIKey=LDCRTTXIJACKKU-SWIHUIHJSA-N
• SMILES: [2H]/C(C(=O)OC)=C(/[2H])C(=O)OC