6,7-Dimethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one

CAS: 1177261-73-2

Ref. TR-D471180

Produktinformation

• Name: 6,7-Dimethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one
• Synonyme: 1-(4-Hydroxy-6,7-dimethoxyquinazolin-2-yl)-4-[[(2RS)-tetrahydrofuran-2-yl]carbonyl]piperazine, Terazosin Hydrochloride Dihydrate Imp. B (EP), 6,7-Dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-4(3H)-quinazolinone
• Marke: TRC
• Beschreibung: Applications 6,7-Dimethoxy-2-(4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl)quinazolin-4(1H)-one is an analogue of Terazosin (T105000), an α-1-adrenergicblocker related to prazosin (P702325).References Patterson, S.E., et al.: J. Chromatog., 311, 206 (1984), Fort, F.L., et al.: Drug Chem. Toxicol., 7, 435 (1984), Lepor, H., et al.: J. Urol., 148, 1467 (1992),

Chemische Eigenschaften

• Molekulargewicht: 388.42
• Formel: C₁₉H₂₄N₄O₅
• Farbe/Form: Off-White
• InChl: InChI=1S/C19H24N4O5/c1-26-15-10-12-13(11-16(15)27-2)20-19(21-17(12)24)23-7-5-22(6-8-23)18(25)14-4-3-9-28-14/h10-11,14H,3-9H2,1-2H3,(H,20,21,24)
• InChI Key: InChIKey=SOPCVLMNPKFJKQ-UHFFFAOYSA-N
• SMILES: COc1cc2[nH]c(N3CCN(C(=O)C4CCCO4)CC3)nc(=O)c2cc1OC