2,2-Dimethylbutanoyl Chloride

CAS: 5856-77-9

Ref. TR-D471465

Produktinformation

• Name: 2,2-Dimethylbutanoyl Chloride
• Synonyme: 2,2-Dimethylbutyric Acid Chloride, 2,2-Dimethylbutyryl Chloride, 2,2-Dimethylbutanoic acid chloride, 2,2-Dimethylbutyl Chloride, 2,2-Dimethylbutyric acid chloride, 2,2-Dimethylbutyryl chloride, Butanoyl chloride, 2,2-dimethyl-, Butyryl chloride, 2,2-dimethyl-

Beschreibung

Applications 2,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 134.6
• Formel: C₆H₁₁ClO
• Farbe/Form: Neat
• InChl: InChI=1S/C6H11ClO/c1-4-6(2,3)5(7)8/h4H2,1-3H3
• InChI Key: InChIKey=LDJUYMIFFNTKOI-UHFFFAOYSA-N
• SMILES: CCC(C)(C)C(=O)Cl