N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N,4-dimethyl-1-naphthalenemethanamine Hydrochloride

CAS: 877265-33-3

Ref. TR-D473215

Produktinformation

• Name: N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N,4-dimethyl-1-naphthalenemethanamine Hydrochloride
• Synonyme: Terbinafine Hydrochloride Imp. D (EP), Terbinafine Imp. D (EP), Terbinafine USP Related Compound D, Terbinafine USP RC D, (2E)-N,6,6-Trimethyl-N-[(4-methylnaphthalen-1-yl)methyl]-hept-2-en-4-yn-1-amine Hydrochloride, Terbinafine Hydrochloride Imp. D (EP) as Hydrochloride, 4-Methylterbinafine Hydrochloride, Terbinafine Related Compound D as Hydrochloride, Terbinafine Hydrochloride Impurity D as Hydrochloride, Terbinafine Impurity D as Hydrochloride, 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N,4-dimethyl-, hydrochloride (1:1), N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N,4-dimethyl-1-naphthalenemethanamine hydrochloride (1:1), 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-ynyl]-N,4-dimethyl-, hydrochloride

Beschreibung

Impurity Terbinafine EP Impurity D; Terbinafine USP Related Compound D; Terbinafine BP Impurity D
Applications N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N,4-dimethyl-1-naphthalenemethanamine (Terbinafine EP Impurity D; Terbinafine USP Related Compound D; Terbinafine BP Impurity D) is an impurity of Terbinafine (T107500), an orally active, antimycotic allylamine and a specific inhibitor of squalene epoxidase.
References Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 341.917
• Formel: C₂₂H₂₇N·ClH
• Farbe/Form: Neat
• InChl: InChI=1S/C22H27N.ClH/c1-18-13-14-19(21-12-8-7-11-20(18)21)17-23(5)16-10-6-9-15-22(2,3)4;/h6-8,10-14H,16-17H2,1-5H3;1H/b10-6+
• InChI Key: InChIKey=HSRZBVGDRJWAFK-SNAWJCMRSA-N
• SMILES: Cc1ccc(CN(C)C/C=C/C#CC(C)(C)C)c2ccccc12.Cl