1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone

CAS: 1193779-48-4

Ref. TR-D475123

Produktinformation

• Name: 1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone
• Synonyme: 2-(tert-Butylamino)-1-(3,5-dichlorophenyl)propan-1-one
• CAS: 1193779-48-4

Beschreibung

Applications 1-(3,5-Dichlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone is an intermediate in the synthesis of 5-Chloro Bupropion Fumarate (C364765). A 5-chloro substitued analogue of Bupropion (B689625) used in the preparation of compounds for indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction.
References Carroll, F.I. et al.: J. Med. Chem., 52, 6768 (2009)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 274.19
• Formel: C₁₃H₁₇Cl₂NO
• Farbe/Form: Neat
• InChl: InChI=1S/C13H17Cl2NO/c1-8(16-13(2,3)4)12(17)9-5-10(14)7-11(15)6-9/h5-8,16H,1-4H3
• InChI Key: InChIKey=ZKFFJBXJJFDBJM-UHFFFAOYSA-N
• SMILES: CC(NC(C)(C)C)C(=O)c1cc(Cl)cc(Cl)c1