Dimethyl (3-phenoxy-2-oxoproyl)phosphonate

CAS: 40665-68-7

Ref. TR-D476695

Produktinformation

• Name: Dimethyl (3-phenoxy-2-oxoproyl)phosphonate
• Synonyme: P-(2-oxo-3-Phenoxypropyl)phosphonic Acid Dimethyl Ester, (2-oxo-3-Phenoxypropyl)phosphonic Acid Dimethyl Ester, (2-Oxo-3-phenoxypropyl)phosphonic Acid Dimethyl Ester, Dimethyl (2-oxo-3-phenoxypropyl)phosphonate, Dimethyl (3-Phenoxyacetonyl)phosphonate, Dimethyl 3-{Phenoxy-2-oxopropylphosphonate, [2-Oxo-3phenoxy-propyl]-phosphonic, Dimethyl (2-Oxo-3-Phenoxypropyl)Phosphonate, (2-Oxo-3-phenoxy-propyl)-phosphonic acid dimethyl ester

Beschreibung

Applications Dimethyl (3-phenoxy-2-oxoproyl)phosphonate Travopropst (T715600), a selective FP prostaglandin receptor agonist. Isopropyl ester of (+)-fluprostenol. Antiglaucoma. Used in the synthesis ofnovel prostanoid thromboxane A2 agonists.
References Mudduluru, H. et al.: Lett. Org. Chem., 8, 234 (2011); Hellberg, M.R., et al.: J. Ocul. Pharmacol. Ther., 17, 421 (2001), McCue, B.A., et al.: J. Pharm. Biomed. Anal., 28, 199 (2002), Schuman, J.S., et al.: Am. J. Ophthalmol., 140, 242 (2005), Carvalho, A.B., et al.: Vet. Ophthalmol., 9, 121 (2006); Joachim, K. et al.: Prostagland., 50, 57 (1995);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 258.21
• Formel: C₁₁H₁₅O₅P
• Farbe/Form: Neat
• InChl: InChI=1S/C11H15O5P/c1-14-17(13,15-2)9-10(12)8-16-11-6-4-3-5-7-11/h3-7H,8-9H2,1-2H3
• InChI Key: InChIKey=NQTSTBMCCAVWOS-UHFFFAOYSA-N
• SMILES: COP(=O)(CC(=O)COc1ccccc1)OC