(2R,4R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester

CAS: 216062-16-7

Ref. TR-D477810

Produktinformation

• Name: (2R,4R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester
• Synonyme: tert-butyl (2R,4R)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-hydroxypyrrolidine-1-carboxylate
• Marke: TRC
• Beschreibung: Applications (2R,4R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of 2’-epi-Lincomycin which is an epimer of Lincomycin (L466200) which is a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity.References Le Goffic, F. et al.: J. Antimicrob. Chemother., 16, 12 (1985); Prior, C. et al.: J. Pharmacol. Exp. Therap., 255, 1170 (1990)

Chemische Eigenschaften

• Molekulargewicht: 331.52
• Formel: C₁₆H₃₃NO₄Si
• Farbe/Form: Neat
• InChl: InChI=1S/C16H33NO4Si/c1-15(2,3)21-14(19)17-10-13(18)9-12(17)11-20-22(7,8)16(4,5)6/h12-13,18H,9-11H2,1-8H3/t12-,13-/m1/s1
• InChI Key: InChIKey=TWNQXBYPAUOYPX-CHWSQXEVSA-N
• SMILES: CC(C)(C)OC(=O)N1C[C@H](O)C[C@@H]1CO[Si](C)(C)C(C)(C)C