3,7-Dimethyl-1-propargylxanthine

CAS: 14114-46-6

Ref. TR-D477850

Produktinformation

• Name: 3,7-Dimethyl-1-propargylxanthine
• Synonyme: 3,7-dimethyl-1-prop-2-ynylpurine-2,6-dione

Beschreibung

Applications A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11± 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 ± 4 uM.
References Alfinito, P., et al.: J. Neurosci., 23, 10982 (2003), Golembiowska, K., et al.: Neuropharmacol., 47, 414 (2004), Solinas, M., et al.: Psychopharmacol., 179, 576 (2005), Panjehpour, M., et al.: Oncol. Res., 16, 575 (2007),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 218.21
• Formel: C₁₀H₁₀N₄O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C10H10N4O2/c1-4-5-14-9(15)7-8(11-6-12(7)2)13(3)10(14)16/h1,6H,5H2,2-3H3
• SMILES: C#CCn1c(=O)c2c(ncn2C)n(C)c1=O