(+)-(3R,4R)-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine

CAS: 119193-19-0

Ref. TR-D479035

Produktinformation

• Name: (+)-(3R,4R)-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine
• Synonyme: 3-[(3R,4R)-3,4-Dimethyl-4-piperidinyl]phenol, (3R-cis)-3-(3,4-dimethyl-4-piperidinyl)phenol, (+)-(3R,4R)-Dimethyl-4-(3-hydroxyphenyl)piperidine, (3R,4R)-3-(3,4-Dimethyl-4-piperidinyl)phenol, (3R,4R)-3-(3,4-dimethyl-4-piperidiny) phenol, 3-((3R,4R)-3,4-dimethylpiperdin-4-yl)phenol, 3-[(3R,4R)-3,4-Dimethylpiperidin-4-yl]phenol, 3-[(3R,4S)-3,4-dimethylpiperidin-4-yl]phenol, Alvimopan Intermediate-1, Phenol, 3-(3,4-dimethyl-4-piperidinyl)-, (3R-cis)-, Phenol, 3-[(3R,4R)-3,4-dimethyl-4-piperidinyl]-
• CAS: 119193-19-0

Beschreibung

Applications (3R,4R)-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine is an intermediate in the preparation of Alvimopan (A575800).
References Carlezon, W., et al.: J. Pharmacol. Exp. Ther., 316, 440 (2006), Carey, A., et al.: Eur. J. Pharmacol., 569, 84 (2007), Cai, T., et al.: J. Med. Chem., 51, 1849 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 205.3
• Formel: C₁₃H₁₉NO
• Farbe/Form: Neat
• InChl: InChI=1S/C13H19NO/c1-10-9-14-7-6-13(10,2)11-4-3-5-12(15)8-11/h3-5,8,10,14-15H,6-7,9H2,1-2H3/t10-,13+/m0/s1
• InChI Key: InChIKey=HXZDAOSDNCHKFE-GXFFZTMASA-N
• SMILES: C[C@H]1CNCC[C@@]1(C)c1cccc(O)c1