1,2-Distearoyl-sn-glycero-3-phosphorylglycerol

CAS: 4537-78-4

Ref. TR-D479240

Produktinformation

• Name: 1,2-Distearoyl-sn-glycero-3-phosphorylglycerol
• Synonyme: [3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-octadecanoyloxypropyl] octadecanoate, Stearin, 1,2-di-, 1-glycerophosphate, Octadecanoic acid, 1,1′-[1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester, Distearoylphosphatidylglycerol, Stearic acid, 3-hydroxypropylene ester hydrogen 2,3-dihydroxypropyl phosphate, Octadecanoic acid, 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester

Beschreibung

Applications 1,2-Distearoyl-sn-glycero-3-phosphorylglycerol is used as a component of a loposomal delivery system that coordinates the release of irinotecan and floxuridine in vivo. It is also used to encapsulate anthracyclines and deliver them to tumors.
References Tardi, P., et al.: Biochimica et Biophysica Acta, Biomembranes, 1768, 678 (2007); Gabizon, A., et al.: J. Drug Targeting, 3, 391 (1996)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 779.076
• Formel: C₄₂H₈₃O₁₀P
• Farbe/Form: Neat
• InChl: InChI=1S/C42H83O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39-40,43-44H,3-38H2,1-2H3,(H,47,48)