5,7-Dinitro-8-quinolinol

CAS: 1084-32-8

Ref. TR-D480280

Produktinformation

• Name: 5,7-Dinitro-8-quinolinol
• Synonyme: 5,7-Bis(hydroxyl[oxido]amino)-8-hydroxyquinoline, 5,7-Dinitro-8-hydroxyquinoline, 5,7-Dinitrooxine, 8-Hydroxy-5,7-dinitroquinoline, NSC 57103, NSC 74940, 8-Quinolinol, 5,7-Dinitro-

Beschreibung

Applications 5,7-Dinitro-8-quinolinol is a useful synthetic intermediate. It has been reported that 5,7-dinitro-8-hydroxyquinoline derivatives exhibit higher antimycobacterial activity than ciprofloxacin (C482500) against M. abscessus and M. Smegmatis. In addition, 5,7-Dinitro-8-quinolinol has been employed to investigate structure-activity relationships of nitroxoline derivatives that may provide new insights on developing novel cathepsin B inhibitors.
References Cieslik, W., et al.: Med Chem. 11, 771 (2015); Sosic, I., et al.: J. Med. Chem. 56, 521 (2013)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 235.15
• Formel: C₉H₅N₃O₅
• Farbe/Form: Neat
• SMILES: O=[N+]([O-])c1cc([N+](=O)[O-])c2cccnc2c1O