Dioscin

CAS: 19057-60-4

Ref. TR-D485230

Produktinformation

• Name: Dioscin
• Synonyme: 3-O-β-D-α-L-Rhamnopyranosyl(1→4)-[α-L-rhamnopyranosyl(1→2)]-β-D-glucopyranoside-diosgenin, Collettiside III, Dioscine, Diosgenin 3-O-α-L-Rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside, Diosgenin 3-O-α-L-Rhamnopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside, Diosgenin bis-α-L-rhamnopyranosyl-(1→2 and 1→4)-β-D-glucopyranoside, Paris III, Polyphyllin III, (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside
• Marke: TRC
• Beschreibung: Applications Dioscin, a natural steroid saponin that has been shown to promote anticancer activity against several forms of cancers. Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins.References Wang, Z., et al.: Land. Biosci., 13, 138 (2012); Shah, H.J., et al.: J. Anal. BIoanal. Tech., 3, 141 (2012); Zhao, X.M., et al.: Toxiciol. Lett., 214, 69 (2012)

Chemische Eigenschaften

• Molekulargewicht: 869.04
• Formel: C₄₅H₇₂O₁₆
• Farbe/Form: Neat
• InChl: InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1