4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol

CAS: 475086-75-0

Ref. TR-D491708

Produktinformation

• Name: 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol
• Synonyme: Isopropylamine Impurity, 4-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol, 4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol

Beschreibung

Applications 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.
References Asaki, T., et al.: Bioorg. Med. Chem., 15, 6692 (2007); Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 361.48
• Formel: C₂₃H₂₇N₃O
• Farbe/Form: Neat
• InChl: InChI=1S/C23H27N3O/c1-18(2)26(15-9-10-16-27)21-17-24-22(19-11-5-3-6-12-19)23(25-21)20-13-7-4-8-14-20/h3-8,11-14,17-18,27H,9-10,15-16H2,1-2H3
• InChI Key: InChIKey=PKBSUZWFQXNCSI-UHFFFAOYSA-N
• SMILES: CC(C)N(CCCCO)c1cnc(-c2ccccc2)c(-c2ccccc2)n1