1-(3-(Dimethylamino)propyl)-1-hydroxy-1,3-dihydroisobenzofuran-5-carbonitrile

CAS: 2102609-59-4

Ref. TR-D495045

Produktinformation

• Name: 1-(3-(Dimethylamino)propyl)-1-hydroxy-1,3-dihydroisobenzofuran-5-carbonitrile
• Synonyme: 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1,3-dihydro-1-hydroxy-, (1RS)-1-[3-(Dimethylamino)propyl]-1-hydroxy-1,3-dihydro-2-benzofuran-5-carbonitrile

Beschreibung

Applications 1-(3-(Dimethylamino)propyl)-1-hydroxy-1,3-dihydroisobenzofuran-5-carbonitrile is an impurity of Citalopram (C505000), an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant. Potent selective serotonin reuptake inhibitor (SSRI).
References Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 246.3049
• Formel: C₁₄H₁₈N₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C14H18N2O2/c1-16(2)7-3-6-14(17)13-5-4-11(9-15)8-12(13)10-18-14/h4-5,8,17H,3,6-7,10H2,1-2H3
• SMILES: CN(C)CCCC1(O)OCc2cc(C#N)ccc21