Dolasetron

CAS: 115956-12-2

Ref. TR-D528500

Produktinformation

• Name: Dolasetron
• Synonyme: 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer, 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2a,6a,8a,9aß)-, 2,6-Methano-2H-quinolizine, 1H-indole-3-carboxylic acid deriv., Anemet, MDL 73147, (2alpha,6alpha,8alpha,9abeta)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-carboxylate, (6R)-3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate, 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2α,6α,8α,9aβ)-, 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, stereoisomer, 1H-indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, 2,6-Methano-2H-quinolizine, 1H-indole-3-carboxylic acid deriv., 3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate, 3-oxooctahydro-2H-2,6-methanoquinolizin-8-yl 1H-isoindole-3-carboxylate, Mdl 73147
• CAS: 115956-12-2

Beschreibung

Applications Bridged pseudopelletierine derivative; specific serotonin (5HT3) receptor antagonist. Antiemetic.
References Boeijinga, P.H., et al.: Eur. J. Pharmacol., 219, 9 (1992), Miller, R.C., et al., Drug Dev. Res., 28, 87 (1993), Fauser, A.A., et al.: Eur. J. Cancer, 32, 1523 (1996), Graczyk, S.G., et al.: Anesth. Analg., 84, 325 (1997),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 324.37
• Formel: C₁₉H₂₀N₂O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C19H20N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,9,11-14,20H,5-8,10H2/t11-,12+,13-,14-
• InChI Key: InChIKey=UKTAZPQNNNJVKR-UHFFFAOYSA-N
• SMILES: O=C(OC1CC2CC3CC(C1)N2CC3=O)c1c[nH]c2ccccc12