Domperidone

CAS: 57808-66-9

Ref. TR-D531100

Produktinformation

• Name: Domperidone
• Synonyme: 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one, Euciton, Evoxin, Gastronorm, KW 5338, Mod, Motilium, NSC 299589, Nauzelin, Nauzelin Ds, Peridon, Peridys, R 33812, 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, 5-Chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazole-2-one, Alpha-[2-(Diisopropylamino) Ethyl]-Alpha-Phenyl-2-Pyridineacetamide, Domcolic, Domperi 10 DT, Domperidon, Domperidona, Kw 5338, Motillium, Motinorm costi, Nomit, Nsc 299589

Beschreibung

Applications A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone (Motilium) is a dopamine blocker and an antidopaminergic reagent.
References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 425.91
• Formel: C₂₂H₂₄ClN₅O₂
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)
• InChI Key: InChIKey=FGXWKSZFVQUSTL-UHFFFAOYSA-N
• SMILES: Oc1nc2ccccc2n1CCCN1CCC(n2c(O)nc3cc(Cl)ccc32)CC1