Domperidone Maleate

CAS: 83898-65-1

Ref. TR-D531118

Produktinformation

• Name: Domperidone Maleate
• Synonyme: 5-Chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one hydrogen (Z)-butenedioate
• Marke: TRC
• Beschreibung: Applications Domperidone maleate (CAS# 99497-03-7); a form of Domperidone (D531100), a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),

Chemische Eigenschaften

• Molekulargewicht: 425.91 + 116.07
• Formel: C₂₂H₂₄ClN₅O₂·C₄H₄O₄
• Farbe/Form: White
• InChl: InChI=1S/C22H24ClN5O2.C4H4O4/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29;5-3(6)1-2-4(7)8/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30);1-2H,(H,5,6)(H,7,8)/b;2-1-
• SMILES: O=C(O)/C=C/C(=O)OC1CN(CCCn2c(=O)[nH]c3ccccc32)CCC1n1c(=O)[nH]c2cc(Cl)ccc21.O=C(O)/C=C\C(=O)OC1CN(CCCn2c(=O)[nH]c3ccccc32)CCC1n1c(=O)[nH]c2cc(Cl)ccc21.O=C(O)C=CC(=O)OC1CN(CCCN2C(=O)[NH2+]c3ccccc32)CCC1N1C(=O)[NH2+]c2cc(Cl)ccc21.O=C([O-])/C=C\C(=O)[O-].O=c1[nH]c2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1