4,​5-​Diphenyl-1H-​imidazole-​2-​propanoic Acid Methyl Ester

CAS: 1075748-68-3

Ref. TR-D683615

Produktinformation

• Name: 4,​5-​Diphenyl-1H-​imidazole-​2-​propanoic Acid Methyl Ester
• Synonyme: methyl 3-(4,5-diphenyl-1H-imidazol-2-yl)propanoate

Beschreibung

Applications 4,​5-​Diphenyl-1H-​imidazole-​2-​propanoic Acid Methyl Ester is an intermediate in the synthesis of 4,5-Diphenyl-1H-imidazole-2-propanoic Acid (D491615) which is an impurity of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).
References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 306.358
• Formel: C₁₉H₁₈N₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C19H18N2O2/c1-23-17(22)13-12-16-20-18(14-8-4-2-5-9-14)19(21-16)15-10-6-3-7-11-15/h2-11H,12-13H2,1H3,(H,20,21)
• InChI Key: InChIKey=ACYSXPPFAIJNSZ-UHFFFAOYSA-N
• SMILES: COC(=O)CCc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1