Duloxetine Maleate

CAS: 116817-86-8

Ref. TR-D721001

Produktinformation

• Name: Duloxetine Maleate
• Synonyme: (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Maleate, (+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine Maleate, LY-248686 Maleate, (S)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine (Z)-2-Butenedioate, 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (S)-, (Z)-2-butenedioate (1:1), 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γS)-, (2Z)-2-butenedioate (1:1)

Beschreibung

Applications Duloxetine Maleate is a dual serotonin and norepinephrine reuptake inhibitor (SNRI) and is used as an antidepressant.
References Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993); Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994); Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 413.49
• Formel: C₂₂H₂₃NO₅S
• Farbe/Form: White to Off-White Solid
• InChl: InChI=1S/C18H19NOS.C4H4O4/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;5-3(6)1-2-4(7)8/h2-10,13,17,19H,11-12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t17-;/m0./s1
• InChI Key: InChIKey=SJYDFHDOQMMHJX-HNUXRKMMSA-N
• SMILES: CNCC[C@H](Oc1cccc2ccccc12)c1cccs1.O=C(O)/C=C\C(=O)O