5-O-Demethyl-28-Oxo-Avermectin A1A

CAS: 102190-68-1

Ref. TR-D722050

Produktinformation

• Name: 5-O-Demethyl-28-Oxo-Avermectin A1A
• Synonyme: Spiro[11,15-Methano-2H,13H,17H-Furo[4,3,2-Pq]

Beschreibung

Applications 5-O-Demethyl-28-oxo-Avermectin A1a is a derivatie of Ivermectin (I940800), which is a semi-synthetic derivative of Abamectin. An invitro inhibitor of SARS-CoV-2/ Covid-19.
References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 887.06
• Formel: C₄₈H₇₀O₁₅
• Farbe/Form: Neat
• InChl: InChI=1S/C48H70O15/c1-11-24(2)42-27(5)17-18-47(63-42)23-32-20-31(62-47)16-15-26(4)41(59-38-22-36(55-10)43(30(8)57-38)60-37-21-35(54-9)40(50)29(7)56-37)25(3)13-12-14-33-45(51)61-44-39(49)28(6)19-34(46(52)58-32)48(33,44)53/h12-15,17-19,24-25,27,29-32,34-44,49-50,53H,11,16,20-23H2,1-10H3/b13-12+,26-15+,33-14+/t24-,25-,27-,29-,30-,31+,32-,34-,35-,36-,37-,38-,39+,40-,41-,42+,43-,44+,47+,48+/m0/s1
• InChI Key: InChIKey=XDZJLYBYTBXNKA-NZWFHOADSA-N
• SMILES: CC[C@H](C)[C@H]1O[C@]2(C=C[C@@H]1C)C[C@@H]1C[C@@H](C/C=C(\C)[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)/C=C/C=C3\C(=O)O[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2