Dutasteride-13C6

CAS: 1217685-27-2

Ref. TR-D735002

Produktinformation

• Name: Dutasteride-13C6
• Synonyme: (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide-13C6, (5a,17ß)-N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-azaandrost -1-ene-17-carboxamide-13C6, Avodart-13C6, Avolve-13C6, GG 745-13C6, GI 198745-13C6, Veltride-13C6

Beschreibung

Applications Labelled Dutasteride (D735000). Dutasteride is a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 534.49
• Formel: C₂₁₁₃C₆H₃₀F₆N₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1/i3+1,5+1,13+1,14+1,18+1,20+1
• InChI Key: InChIKey=JWJOTENAMICLJG-JADBXJRRSA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@H]4NC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2C(=O)N[13c]1[13cH][13c](C(F)(F)F)[13cH][13cH][13c]1C(F)(F)F