2,3-Dihydro-1-oxo Asenapine

CAS: 934996-79-9

Ref. TR-D856510

Produktinformation

• Name: 2,3-Dihydro-1-oxo Asenapine
• Synonyme: 5-Chloro-2,3-dihydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole

Beschreibung

Applications 2,3-Dihydro-1-oxo Asenapine is an intermediate of Asenapine(A788000) which is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist; structurally related to Mianserin. Antipsychotic.
References Meltzer, H., et al.: J. Pharmacol. Exp. Ther., 251, 238 (1989), Schotte, A., et al.: Brain Res., 631, 191 (1993), Andree, B., et al.: Psychopharmacology, 131, 339 (1997), Richelson, E., et al.: Life Sci., 68, 29 (2000),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 297.74
• Formel: C₁₇H₁₂ClNO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C17H12ClNO2/c1-19-9-13-12-8-10(18)6-7-15(12)21-14-5-3-2-4-11(14)16(13)17(19)20/h2-8H,9H2,1H3
• InChI Key: InChIKey=ASVOBJGTTRHXOD-UHFFFAOYSA-N
• SMILES: CN1CC2=C(C1)c1cc(Cl)ccc1Oc1ccccc12