2-(1-Ethylpropyl)-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one

CAS: 212632-01-4

Ref. TR-E184180

Produktinformation

• Name: 2-(1-Ethylpropyl)-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one
• Synonyme: 4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-pentan-3-yl-1,2,4-triazol-3-one
• Marke: TRC
• Beschreibung: Applications 2-(1-Ethylpropyl)-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one is an intermediate in the synthesis of Deshydroxy Posaconazole Impurity (A6480252), which is a 2,2,5-tetrahydrofuran regioisomers of SCH 51048 (A648025) that exhibit antifungal activity.References Lovey, R.G.; et al.: Bioorganic Med. Chem. Lett, 12, 1739 (2002)

Chemische Eigenschaften

• Molekulargewicht: 407.509
• Formel: C₂₃H₂₉N₅O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C23H29N5O2/c1-3-18(4-2)28-23(30)27(17-24-28)21-7-5-19(6-8-21)25-13-15-26(16-14-25)20-9-11-22(29)12-10-20/h5-12,17-18,29H,3-4,13-16H2,1-2H3
• InChI Key: InChIKey=KWEIEPKOLYAFKI-UHFFFAOYSA-N
• SMILES: CCC(CC)n1ncn(-c2ccc(N3CCN(c4ccc(O)cc4)CC3)cc2)c1=O