Ebastine

CAS: 90729-43-4

Ref. TR-E320000

Produktinformation

• Name: Ebastine
• Synonyme: 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone, Bastel, Ebastel, Ebastin, LAS-W 090, RP 64305, 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone, 1-(4-Tert-Butylphenyl)-4-[4-(Diphenylmethoxy)Piperidin-1-Yl]Butan-1-One, 1-Butanone, 1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-, 4'-tert-Butyl-4-(4-(diphenylmethoxy)piperidino)butyrophenone, 4-Diphenylmethoxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine, Ebastina, Ebastina [Spanish], Ebastine [USAN:INN], Ebastinum, Ebastinum [Latin], Erostin, Kestine, Las W-090, Rp 64305, Unii-Tqd7Q784P1

Beschreibung

Applications A nonsedating type histamine H1-receptor antagonist. Antihistaminic.
References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Inomata, N., et al.: J. Dermatol., 36, 224 (2009), Carvajal, A., et al.: Clin. Pharmacol. Ther., 85, 481 (2009), Yamashita, S., et al.: Mol. Pharm., 6, 48 (2009),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 469.66
• Formel: C₃₂H₃₉NO₂
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C32H39NO2/c1-32(2,3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-9,11-14,16-19,29,31H,10,15,20-24H2,1-3H3
• InChI Key: InChIKey=MJJALKDDGIKVBE-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1ccc(C(=O)CCCN2CCC(OC(c3ccccc3)c3ccccc3)CC2)cc1