Eltrombopag Ethyl Ester

Ref. TR-E508010

Produktinformation

• Name: Eltrombopag Ethyl Ester
• Synonyme: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Ethyl Ester
• Marke: TRC
• Beschreibung: Applications Eltrombopag Ethyl Ester, is a metabolite of Eltrombopag (E508000), which is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.References Bussel, J., et al.: New Eng. J. Med., 357, 2237 (2007), Marsilje, T., et al.: Bioorg. Med. Chem. Lett., 18, 5259 (2008), Alper, P., et al.: Bioorg. Med. Chem. Lett., 18, 5255 (2008),

Chemische Eigenschaften

• Molekulargewicht: 470.52
• Formel: C₂₇H₂₆N₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C27H26N4O4/c1-5-35-27(34)20-9-6-8-19(15-20)22-10-7-11-23(25(22)32)28-29-24-18(4)30-31(26(24)33)21-13-12-16(2)17(3)14-21/h6-15,30,32H,5H2,1-4H3
• InChI Key: InChIKey=QUMJLRPNZDVSRC-OLFWJLLRSA-N
• SMILES: CCOC(=O)c1cccc(-c2cccc(N/N=C3\C(=O)N(c4ccc(C)c(C)c4)N=C3C)c2O)c1