Entacapone-d10

CAS: 1185241-19-3

Ref. TR-E558502

Produktinformation

• Name: Entacapone-d10
• Synonyme: 2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-bis(1,1,2,2,2-pentadeuterioethyl)prop-2-enamide, 2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-di(ethyl-d5)-2-propenamide, Entacapone-D10 (N,N-di(ethyl-D5))

Beschreibung

Applications (E)-Isomer of labelled Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
References Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 315.35
• Formel: C₁₄H₅D₁₀N₃O₅
• Farbe/Form: Light Yellow To Dark Orange
• InChl: InChI=1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/i1D3,2D3,3D2,4D2
• SMILES: [2H]C([2H])([2H])C([2H])([2H])N(C(=O)/C(C#N)=C/c1cc(O)c(O)c([N+](=O)[O-])c1)C([2H])([2H])C([2H])([2H])[2H]