Eplerenone-d3

CAS: 107724-20-9

Ref. TR-E588777

Produktinformation

• Name: Eplerenone-d3
• Synonyme: (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid, γ-Lactone 7-(Methyl-d3) Ester, CGP 30083-d3, Epoxymexrenone-d3, Inspra-d3, SC-66110-d3
• Marke: TRC

Beschreibung

Applications Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),

Chemische Eigenschaften

• Molekulargewicht: 417.51
• Formel: C₂₄H₂₇D₃O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17-,19+,21+,22+,23-,24?/m1/s1/i3D3
• InChI Key: InChIKey=JUKPWJGBANNWMW-WAICZPKKSA-N
• SMILES: [2H]C([2H])([2H])OC(=O)[C@@H]1CC2=CC(=O)CC[C@]2(C)C23O[C@@H]2C[C@@]2(C)[C@@H](CC[C@@]24CCC(=O)O4)[C@H]13