4-(2,3-Epoxypropoxy-d5)carbazole

CAS: 51997-51-4

Ref. TR-E589252

Produktinformation

• Name: 4-(2,3-Epoxypropoxy-d5)carbazole
• Synonyme: 4-Oxiranylmethoxy-d5-9H-carbazole, 4-(Oxiranylmethoxy-d5)-9H-carbazole, 4-(2,3-Epoxy Propoxy) Carbazole, 4-(2,3-Epoxy Proxy) Carbazole, 4-(2,3-Epoxyporpaneoxy)Carbazo, 4-(2,3-Epoxyporpanoxy)-Carbazole, 4-(2,3-Epoxypropaneoxy)Carbazole, 4-(2,3-Epoxypropanoxy)Carbazole, 4-(2,3-Epoxypropoxy)-9h-Carbazole, 4-(2-Oxiranylmethoxy)-9h-Carbazole, 4-(Glycidyloxy)carbazole, 4-(oxiran-2-ylmethoxy)-9H-carbazole, 4-Epoxypropanoxycarbazole, 4-Glycidyloxycarbazole, 4-Oxiranylmethoxy-9h-Carbazole, 9H-Carbazole, 4-(2-oxiranylmethoxy)-, 9H-Carbazole, 4-(oxiranylmethoxy)-, Carvedilol Intermediates

Beschreibung

Applications 4-(2,3-Epoxypropoxy-d5)carbazole is the labeled analogue of 4-(2,3-Epoxypropoxy)carbazole (E589250), an intermediate in the synthesis of Carvedilol (C184625), a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.
References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 244.3
• Formel: C₁₅D₅H₈NO₂
• Farbe/Form: Off-White
• InChl: InChI=1S/C15H13NO2/c1-2-5-12-11(4-1)15-13(16-12)6-3-7-14(15)18-9-10-8-17-10/h1-7,10,16H,8-9H2/i8D2,9D2,10D
• InChI Key: InChIKey=SVWKIGRDISDRLO-GFWWIRCNSA-N
• SMILES: [2H]C([2H])(Oc1cccc2[nH]c3ccccc3c12)C1([2H])OC1([2H])[2H]