Epoxyazadiradione

CAS: 18385-59-6

Ref. TR-E590018

Produktinformation

• Name: Epoxyazadiradione
• Synonyme: Nimbinin, 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, 24-norchola-1,20,22-triene-3,16-dione deriv., Azadiradione 14ß,15ß-Epoxide, (5Alpha,13Xi,14Beta,15Beta)-17-(Furan-3-Yl)-4,4,8-Trimethyl-3,16-Dioxo-14,15-Epoxyandrost-1-En-7-Yl Acetate, (5alpha,7alpha,13alpha,14beta,15beta,17alpha)-7-(Acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-24-norchola-1,20,22-triene-3,16-dione, (5α,7α,13α,14β,15β,17α)-7-(Acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-24-norchola-1,20,22-triene-3,16-dione, 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, 24-norchola-1,20,22-triene-3,16-dione deriv., 24-Nor-5α,13α,14β,17α-chola-1,20,22-triene-3,16-dione, 14,15β:21,23-diepoxy-7α-hydroxy-4,4,8-trimethyl-, acetate, 24-Norchola-1,20,22-triene-3,16-dione, 7-(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-, (5alpha,7alpha,13alpha,14beta,15beta,17alpha)-, 24-Norchola-1,20,22-triene-3,16-dione, 7-(acetyloxy)-14,15:21,23-diepoxy-4,4,8-trimethyl-, (5α,7α,13α,14β,15β,17α)-, Azadiradione 14β,15β-epoxide, Azadiradione, epoxy-, Nsc 640467

Beschreibung

Applications Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NFkB in human cervical cancer cells.
References Shilpa, G. et al.: Phytother. Res., 31, 1892 (2017);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 466.56
• Formel: C₂₈H₃₄O₆
• Farbe/Form: Off-White
• InChl: InChI=1S/C28H34O6/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)22(31)23-28(26,34-23)27(17,20)6/h8-10,12,14,17-18,20-21,23H,7,11,13H2,1-6H3/t17-,18+,20-,21-,23-,25-,26+,27+,28-/m1/s1
• InChI Key: InChIKey=NEYCGDYQBQONFC-GGPFZBFUSA-N
• SMILES: CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@H](c4ccoc4)C(=O)[C@H]4O[C@]43[C@]12C