(9E)-Erythromycin A Oxime

CAS: 111321-02-9

Ref. TR-E650035

Produktinformation

• Name: (9E)-Erythromycin A Oxime
• Synonyme: Erythromycin A 9-(E)-oxime, Erythromycin 9-(E)-oxime, Oxacyclotetradecane, erythromycin deriv., (E)-Erythromycin A oxime, (E)-Erythromycin oxime, Clarithromycin Imp. J (EP), Unii-10W452Cmtz, Erythromycin, 9-oxime, Erythromycin A Oxime, (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime (non-preferred name)

Beschreibung

Applications (9E)-Erythromycin A Oxime is a metabolite of Roxithromycin (R700850) in humans. It has anti-Helicobacter pylori activity
References Nam, G. et al.: Bioorg. Med. Chem. Lett., 16, 569 (2006); Zhong, D. et al.: Drug Metab. Dispos., 28, 552 (2000); Yamazaki, H. et al.: Drug. Metab. Dispos., 26, 1053 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 748.94
• Formel: C₃₇H₆₈N₂O₁₃
• Farbe/Form: Neat
• InChl: InChI=1S/C37H68N2O13/c1-14-25-37(10,45)30(41)20(4)27(38-46)18(2)16-35(8,44)32(52-34-28(40)24(39(11)12)15-19(3)48-34)21(5)29(22(6)33(43)50-25)51-26-17-36(9,47-13)31(42)23(7)49-26/h18-26,28-32,34,40-42,44-46H,14-17H2,1-13H3/b38-27+/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1