Erythromycin Lactobionate

CAS: 3847-29-8

Ref. TR-E650040

Produktinformation

• Name: Erythromycin Lactobionate
• Synonyme: Erythromycin A Lactobionate, (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-l-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-ß-d-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione 4-O-ß-d-galactopyranosyl-d-gluconate, (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}hexanoic acid - (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (1:1) (non-preferred name), 4-O-beta-D-Galactopyranosyl-D-gluconic acid compd. with erythromycin, <span class="text-smallcaps">D</smallcap>-Gluconic acid, 4-O-β-<smallcap>D</span>-galactopyranosyl-, compd. with erythromycin (1:1), D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, compd. with erythromycin (1:1) (9CI), Erythrocin Lactobionate IV, Erythrocin lactobionate, Erythromycin lactobionate (1:1) (salt), Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt), Erythromycin, 4-O-beta-D-galactopyranosyl-D-gluconate (salt), Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (1:1), Erythromycin, 4-O-β-<span class="text-smallcaps">D</smallcap>-galactopyranosyl-<smallcap>D</span>-gluconate (salt), Erythromycin. compd. with lactobionic acid, Lactobionic acid, compd. with erythromycin (1:1), Oxacyclotetradecane, erythromycin deriv.
• CAS: 3847-29-8

Beschreibung

Applications Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.
References Kiso, S. et al.: Anticanc. Res., 20, 2827 (2000); Broad, J. et al.: Brit. J. Pharm., 168,1859 (2013); Itoh, Z., et al.: Antimicrob. Agents Chemother., 26, 863(1984)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 1092.22
• Formel: C₃₇H₆₇NO₁₃·C₁₂H₂₂O₁₂
• Farbe/Form: Neat
• InChl: 3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-, InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26, 13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3, 3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1
• InChI Key: InChIKey=NNRXCKZMQLFUPL-DTZNXKQASA-N
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O.O=C(O)[C@H](O)[C@@H](O)C(O[C@@H]1OC(CO)[C@H](O)C(O)C1O)[C@H](O)CO