Estriol Methyl Ether

CAS: 1474-53-9

Ref. TR-E668660

Produktinformation

• Name: Estriol Methyl Ether
• Synonyme: 3-Methoxyestra-1,3,5(10)-triene-16alpha,17beta-diol, Estra-1,3,5(10)-triene-16,17-diol, 3-methoxy-, (16alpha,17beta)-, Estra-1,3,5(10)-triene-16alpha,17beta-diol, 3-methoxy- (6CI,7CI,8CI), (16alpha,17beta)-3-Methoxyestra-1,3,5(10)-triene-16,17-diol, 13beta-Methyl-3-methoxygona-1,3,5(10)triene-16alpha,17beta-diol, 16alpha,17beta-Estriol-3-methyl ether, 3-Methoxyestriol, E 2710, Estriol 3-methyl ether, Estriol Impurity C,3-Methoxyestra-1,3,5(10)-triene-16a,17ß-diol (Estriol 3-Methyl Ether), Estriol Imp. C (EP), (16Alpha)-3-Methoxyestra-1,3,5(10)-Triene-16,17-Diol, (16Alpha,17Beta)-3-Methoxyestra-1,3,5(10)-Triene-16,17-Diol, (16α,17β)-3-Methoxyestra-1,3,5(10)-triene-16,17-diol, 13β-Methyl-3-methoxygona-1,3,5(10)triene-16α,17β-diol, 16α,17β-Estriol-3-methyl ether, Estra-1,3,5(10)-triene-16,17-diol, 3-methoxy-, (16α,17β)-, Estra-1,3,5(10)-triene-16-alpha,17-beta-diol, 3-methoxy-, Estra-1,3,5(10)-triene-16α,17β-diol, 3-methoxy-, Estriol methyl ether

Beschreibung

Impurity Estriol EP Impurity C
Applications Estriol Methyl Ether (Estriol EP Impurity C) is a metabolite (1,2) of Estriol (E888960), which is a produced naturally and also a metabolite of Estradiol (E888000). Estriol is a GPR3 antagonist in estrogen receptor-negative breast cancer cells displaying anti-proliferative effects (3).
References 1. Marrian, G. et al.: Biochem. J. 1929;23(5):1090-8.2. Rogerson, B. et al.: Arch. Biochem. Biophys. 1986 Oct;250(1):70-85.3. Lappano, R. et al.: Mol Cell Endocrinol. 2010 May 14;320(1-2):162-70.

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 302.41
• Formel: C₁₉H₂₆O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C19H26O3/c1-19-8-7-14-13-6-4-12(22-2)9-11(13)3-5-15(14)16(19)10-17(20)18(19)21/h4,6,9,14-18,20-21H,3,5,7-8,10H2,1-2H3/t14-,15-,16+,17-,18+,19+/m1/s1
• InChI Key: InChIKey=UHQGCIIQUZBJAE-QKDSSNGWSA-N
• SMILES: COc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1C[C@@H](O)[C@@H]2O