(11b,​17a)​-17-​[(Ethoxycarbonyl)​oxy]​-​11-​hydroxy-​3-​oxo-​androsta-​1,​4-​diene-​17-​carboxylic Acid

CAS: 133991-63-6

Ref. TR-E890570

Produktinformation

• Name: (11b,​17a)​-17-​[(Ethoxycarbonyl)​oxy]​-​11-​hydroxy-​3-​oxo-​androsta-​1,​4-​diene-​17-​carboxylic Acid
• Synonyme: PJ 91, Dechloromethyl Loteprednol Etabonate
• CAS: 133991-63-6

Beschreibung

Stability Hygroscopic
Applications (11β,​17α)​-17-​[(Ethoxycarbonyl)​oxy]​-​11-​hydroxy-​3-​oxo-​androsta-​1,​4-​diene-​17-​carboxylic acid is a derivative of Loteprednol Etabonate (L471400) which is an ophthalmic corticosteroid.
References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 418.48
• Formel: C₂₃H₃₀O₇
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C23H30O7/c1-4-29-20(28)30-23(19(26)27)10-8-16-15-6-5-13-11-14(24)7-9-21(13,2)18(15)17(25)12-22(16,23)3/h7,9,11,15-18,25H,4-6,8,10,12H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,21-,22-,23-/m0/s1
• InChI Key: InChIKey=CCMMQGHLQQKWOY-NGVSTBRYSA-N
• SMILES: CCOC(=O)O[C@]1(C(=O)O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C