N-(Ethoxycarbonylmethyl)piperazine

CAS: 40004-08-8

Ref. TR-E891400

Produktinformation

• Name: N-(Ethoxycarbonylmethyl)piperazine
• Synonyme: 1-Piperazineacetic Acid Ethyl Ester, 2-(Piperazin-1-yl)acetic Acid Ethyl Ester, 4-(Carboethoxymethyl)piperazine, Ethyl 1-piperazineacetate, Ethyl 1-Piperazinylacetate, Ethyl 2-(piperazin-1-yl)acetate, Ethyl 2-Piperazinoacetate, Ethyl Piperazinoacetate, N-(Carboethoxymethyl)piperazine, Piperazin-1-ylacetic Acid Ethyl Ester, (1-Piperazino)acetic acid ethyl ester, 1-(Ethoxycarbonylmethyl)piperazine, 1-Piperazineacetic acid, ethyl ester, 2-(Piperazin-1-yl)acetic acid ethyl ester, Ethyl (1-piperazino)acetate, Ethyl 1-piperazinylacetate, Ethyl 2-piperazinoacetate, Ethyl Piperazin-1-Ylacetate, Ethyl piperazinoacetate, Piperazin-1-ylacetic acid ethyl ester

Beschreibung

Applications N-(Ethoxycarbonylmethyl)piperazine is used in the preparation of aralkylpiperazine- and aryl-substituted hydrazines, particularly benzylpiperazineacetyl hydrazones of hydroxyaryl aldehydes, as selective inducers of apoptosis and activators of procaspases for use as anticancer agents.
References Nakagawara, A., et al.: Cancer Res., 57, 4578 (1997), Denault, J., et al.: J. Biol. Chem., 278, 34042 (2003), Traven, A., et al.: Cancer Cell, 5, 107 (2004), Becattini, B., et al.: Chem. Biol., 11, 389 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 172.22
• Formel: C₈H₁₆N₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C12H15N3O4/c1-10(16)19-9-15(14-18)7-3-5-12(17)11-4-2-6-13-8-11/h2,4,6,8H,3,5,7,9H2,1H3
• InChI Key: InChIKey=PGOGEOISASKDLL-UHFFFAOYSA-N
• SMILES: CC(=O)OCN(CCCC(=O)c1cccnc1)N=O