5,8-cis-5,8-Epoxy-13-cis Retinoic Acid

Ref. TR-E892120

Produktinformation

• Name: 5,8-cis-5,8-Epoxy-13-cis Retinoic Acid
• Synonyme: (2Z,4E,6E)-7-[(2S,7aR)-4,4,7a-trimethyl-2,5,6,7-tetrahydro-1-benzofuran-2-yl]-3-methylocta-2,4,6-trienoic acid

Beschreibung

Applications 5,8-cis-5,8-Epoxy-13-cis Retinoic Acid can be obtained from 13-cis-Retinoic Acid (R250000) which is used as a treatment for severe acne. Presently being studied in conjunction with the treatment of photoaged skin.
References Lerche, C., et al.: Exp. Dermatol., 17, 972 (2008), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Gan, J., et al.: Chem. Res. Toxicol., 22, 690 (2009), Macejova, D., et al.: Toxicol. Lett., 184, 114 (2009), Chen, P., et al.: Toxicol. App. Pharmacol., 234, 143 (2009),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 316.435
• Formel: C₂₀H₂₈O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C20H28O3/c1-14(12-18(21)22)8-6-9-15(2)16-13-17-19(3,4)10-7-11-20(17,5)23-16/h6,8-9,12-13,16H,7,10-11H2,1-5H3,(H,21,22)/b8-6+,14-12-,15-9+/t16-,20+/m0/s1
• InChI Key: InChIKey=QDOSIDVGVRAXSE-GWULVECFSA-N
• SMILES: CC(=C/C(=O)O)/C=C/C=C(\C)[C@@H]1C=C2C(C)(C)CCC[C@@]2(C)O1