7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin

CAS: 185304-42-1

Ref. TR-E899150

Produktinformation

• Name: 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin
• Synonyme: 4-Amino-(4S)-4,11-diethyl-3,4,12,14-tetrahydro
• Marke: TRC
• Beschreibung: Stability Light Sensitive, Moisture Sensitive, Temperature SensitiveApplications A major metabolite of Irinotecan.References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),

Chemische Eigenschaften

• Molekulargewicht: 518.56
• Formel: C₂₈H₃₀N₄O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C28H30N4O6/c1-3-17-18-11-16(38-27(35)31-9-7-15(29)8-10-31)5-6-22(18)30-24-19(17)13-32-23(24)12-21-20(25(32)33)14-37-26(34)28(21,36)4-2/h5-6,11-12,15,36H,3-4,7-10,13-14,29H2,1-2H3/t28-/m0/s1
• InChI Key: InChIKey=APWFTHDYKJHNEV-NDEPHWFRSA-N
• SMILES: CCc1c2c(nc3ccc(OC(=O)N4CCC(N)CC4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC