7-Ethyl Camptothecin

CAS: 78287-27-1

Ref. TR-E900830

Produktinformation

• Name: 7-Ethyl Camptothecin
• Synonyme: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4-hydroxy-, (4S)-, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-4-hydroxy-, (S)-, 7-Ethyl-20(S)-camptothecin, 7-Ethylcamptothecin, SN 22
• Marke: TRC

Beschreibung

Impurity Irinotecan USP Related Compound E
Applications An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E.
References Brangi, M., et al.: Cancer Res., 59 5938 (1999), Miyake, K., et al.: Cancer Res., 59, 8 (1999) , Bom, D., et al.: J. Med. Chem., 43, 3970 (2000) , Gamcsik, M., et al.: Mol. Cancer Ther., 1, 11 (2001).

Chemische Eigenschaften

• Molekulargewicht: 376.41
• Formel: C₂₂H₂₀N₂O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1
• InChI Key: InChIKey=MYQKIWCVEPUPIL-QFIPXVFZSA-N
• SMILES: CCc1c2c(nc3ccccc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC