Ethyl 5-(2-Hydroxy-4,5-dimethoxybenzamido)thiophene-3-carboxylate

CAS: 185106-05-2

Ref. TR-E919168

Produktinformation

• Name: Ethyl 5-(2-Hydroxy-4,5-dimethoxybenzamido)thiophene-3-carboxylate

Beschreibung

Applications Ethyl 5-(2-Hydroxy-4,5-dimethoxybenzamido)thiophene-3-carboxylate is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats (1,2). Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
References Masanao, K., et. al.: Eur. J. Pharmacol., 666, 218 (2011); Matsunaga, Y., et. al.: J. Pharmacol. Exp. Ther., 336, 791 (2011)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 352.36
• Formel: C₁₅H₁₆N₂O₆S
• Farbe/Form: White to Off-White Solid
• InChl: InChI=1S/C10H7F3O/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1-7H/b4-2+
• InChI Key: InChIKey=JMKMLIWUWJNVIG-DUXPYHPUSA-N
• SMILES: O=C/C=C/c1cccc(C(F)(F)F)c1