Etravirine

CAS: 269055-15-4

Ref. TR-E937000

Produktinformation

• Name: Etravirine
• Synonyme: 4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile, 4-((6-Amino-5-Bromo-2-((4-Cyanophenyl)Amino)-4-Pyrimidinyl)Oxy)-3,5-Dimethyl-Benzonitrile, 4-(6-Amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile, 4-({6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]Pyrimidin-4-Yl}Oxy)-3,5-Dimethylbenzonitrile, 4-({6-Amino-5-brom-2-[(4-cyanphenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzolcarbonitril, 4-[[6-Amino-5-Bromo-2-[(4-Cyanophenyl)Amino]-4-Pyrimidinyl]Oxy]-3,5�CDimethylbenzonitrile, 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile, 6-Amino-5-Bromo-4-(4-Cyano-2,6-Dimethylphenoxy)-2-(4-Cyanophenylamino)Pyrimidine, Benzonitrile, 4-((6-amino-5-bromo-2-((4-cyanophenyl)amino)-4-pyrimidinyl)oxy)-3,5-dimethyl-, Etravirine [INN], Etravirine [USAN:INN], Intelence, R 165335, R165335-Tmc125, Tmc 125, Tmc125, Unii-0C50Hw4Fo1

Beschreibung

Applications Etravirine is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection.
References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008), Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 435.28
• Formel: C₂₀H₁₅BrN₆O
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)
• SMILES: Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1Br